Nature has a long track record of being a source of compounds that led to FDA-approved drugs. Fungi, in particular, may have had one of the biggest impacts on survival rates in the 20th century due to the discovery of penicillin and the antibiotics revolution that it stimulated. In fact, you would be hard pressed to find anyone in the world who has not been treated with an antibiotic at least once in their lifetimes. However, much of the work that led to modern antibiotics was carried out in the 1950s through 1980s. Have you ever wondered how someone goes about ‘discovering’ a drug lead from fungi in 2023? This talk will go into details about how fungi, collected from the environment, are used as a source for drug leads, particularly for the sake of anticancer drug discovery, by telling you how this is carried out in a project that is currently funded by the National Cancer Institute.
Watch the recording on YouTube.
Dr. Nicholas Oberlies is an internationally recognized expert in the chemistry of nature and medicines from natural products. Leads a team of scientists focused on the discovery of new drug leads. Skilled in the discovery, biological evaluation, structure elucidation, and optimization of natural product drug leads.
Consulted on the analysis of natural products (e.g., setting up drug discovery pipelines and determining safety of herbal remedies) for clients ranging from Fortune 500 corporations (e.g. Procter & Gamble) to biotechs. Served as a qualified expert witness. Trained chemistry students in communication skills and public speaking. Developed workshops on Scientific Entrepreneurship. Served on Scientific Advisory Boards for Mycosynthetix, Ionic Pharmaceuticals, Clue Genetics and several Journals (e.g., J. Antibiotics, Phytochemistry, Planta Medica). Over 100 invited scientific presentations, both nationally and internationally. Published >220 manuscripts.


Emily Catherine Egan is Assistant Professor of Ancient Eastern Mediterranean Art and Archaeology in the Department of Art History & Archaeology at the University of Maryland. She holds a dual B.A. from Brown University in Classics and Old World Archaeology and Art, an M.Phil. in Archaeology from the University of Cambridge, and an M.A. and Ph.D. from the Department of Classics at the University of Cincinnati. She has conducted archaeological fieldwork in Italy, Turkey, Cyprus, Jordan, Armenia, and Greece, where she is currently involved in projects at the sites of Mycenae and Pylos. Her research focuses on painted surface decoration, and especially on the iconography of Greek wall and floor paintings from the late second millennium BC.
Dann Woellert is a Food Etymologist, studying the origin of our food customs and regional dishes. From discovering the region in northwest Germany where our Goetta originated, to breaking down the Cincinnati style three-way, Dann takes us on a journey of discovery and connection to our ancestors. For the last decade he has curated the blog Dann Woellert the Food Etymologist and has written eight books about Cincinnati Food History. He has recently been in five episodes of Season 4’s Food that Built America on the History Channel (streaming on Hulu and Amazon). He’s a history preservationist and is closely tied to several local organizations including the Delhi, Cheviot, Westwood, Price Hill, Milford, Loveland and Green Township Historical Society, the German Heritage and Over-the-Rhine Museums, and the Brewery Heritage Trail. Dann also teaches at UC’s Communiversity and has been seen dressed in Civil War uniform, as St. Nicholas, and as beer baron Fred Linck around town.